Summary
A postdoctoral fellowship position in cancer immunology and
immunotherapy is available at the Center for Advanced Innate Cell
Therapy within the Texas Children's Cancer Center. The project aims
to develop and test novel CAR-redirected immunotherapy for
pediatric solid tumors. In particular, a CRISPR/Cas9-based
mutagenesis screen will be applied to discover and therapeutically
target novel regulators of the immune effector cell antitumor
activity. We offer outstanding state-of-the-art, recently expanded
laboratory facilities and a highly interactive environment for
basic, translational, and clinical investigators. Candidates must
have a recent PhD degree and an expertise in molecular biology and
tumor immunology with a documented record of productivity.
Job Duties
- Designs and conducts the experiments related to the project
with the help of the mentor and other team members.
- Analyzes the data and presents the evolving results at weekly
laboratory meetings and research seminars of the Center for
Advanced Innate Cell Therapy and the Center for Cell and Gene
Therapy. The details of the experiments and the findings will be
recorded in electronic laboratory notebook.
- Writes technical reports and manuscripts for publication in
peer-reviewed scientific journals.
Minimum Qualifications
- MD or Ph.D. in Basic Science, Health Science, or a related
field.
- No experience required.
Preferred Qualifications
- Ph.D. in immunology, genetic engineering or related
fields.
- Great fund of knowledge of tumor immunology principles.
- Ability to assess scRNAseq datasets and highly parametric flow
cytometry.
- Understanding and practicing genetic engineering techniques
(transfection, retroviral / lentiviral transduction, transposition,
CRISPR-Cas9).
- Viral particle assembly.
- Excellent aseptic cell culture technique.
- Enthusiasm and a willingness to learn in a fast-pace,
collaborative environment.
- Strong organizational skills, record keeping, and interpersonal
communication skills (verbal and written).
Baylor College of Medicine is an Equal Opportunity/Affirmative
Action/Equal Access Employer.
Requisition ID: 21213
